Dr. John Krystal

Dr. John Krystal is best known for the discovery of the rapid antidepressant effects of ketamine in patients (2000) and the invention of Esketamine, which directly led to FDA approval of Jannsen’s Spravato Esketamine spray, the first novel antidepressant in 50 years (Esketamine, 2019). John is also one of the top experts in the neurobiology and treatment of alcoholism and PTSD. Most recently, he co-founded the National PTSD Brain Bank and co-led the first transcriptomic studies of PTSD.